When your dog is sick, drooling, and not eating, it’s a sign something is seriously off. When these symptoms occur together, it’s time to pay close attention.
We outline the common causes of a dog being sick, drooling, and not eating, what you can do at home, and when to seek veterinary help.
Dog Sick, Drooling, Not Eating — Why It Happens
When a dog is sick, drooling, and not eating, it usually means the digestive system or another major organ is under stress. These symptoms often appear together in cases of nausea, pancreatitis, liver or kidney problems, dental disease, or poisoning.
Dogs drool when they feel nauseous, and refusing food is a common reaction when the stomach or internal organs are irritated.
The combination of vomiting, drooling, and appetite loss shouldn’t be ignored, as it may point to a serious underlying condition that requires veterinary attention.

Dog Sick, Drooling, Not Eating: Common Causes
Pancreatitis
Pancreatitis is one of the most common reasons for a dog being sick, drooling, and not eating. It occurs when the pancreas becomes inflamed, often after eating fatty food, garbage, or something toxic.
A dog with pancreatitis may vomit repeatedly, have a painful abdomen, drool heavily from nausea, and refuse food entirely. Some dogs may pace or stretch frequently to relieve abdominal discomfort.
Pancreatitis can become life-threatening if untreated, as it can cause dehydration, internal infection, and systemic inflammation.
Veterinary care typically includes IV fluids, anti-nausea medication, and a temporary fasting period to let the pancreas rest.
Read more: Dog Sick Diarrhea and Not Eating (Here’s what it means)
Gastroenteritis
Gastroenteritis, or inflammation of the stomach and intestines, is another common cause of vomiting, drooling, and appetite loss.
It can result from eating spoiled food, a sudden diet change, bacterial infections, or even stress. Drooling often precedes vomiting because of nausea, and dogs may also have diarrhea or appear weak and dehydrated.
While mild cases may resolve with rest and a bland diet, persistent vomiting or refusal to eat for more than 24 hours warrants a vet visit. Dehydration can set in quickly, especially in smaller breeds.
Liver Disease
Liver problems can cause nausea, vomiting, drooling, and appetite loss in dogs. The liver plays a crucial role in detoxifying the body, and when it’s not functioning properly, toxins build up in the bloodstream.
You may notice yellowing of the gums or eyes (jaundice), lethargy, or pale stools. Dogs may also drool excessively due to nausea and develop a distended belly from fluid buildup.
Liver disease requires professional diagnosis through blood tests and imaging. Treatment may include medication, diet changes, and supportive care to reduce toxin levels and inflammation.
Toxin or Foreign Object Ingestion
If your dog suddenly becomes sick, drooling, and refuses to eat, toxin exposure or swallowing a foreign object should be high on your list of concerns.
Common toxins include chocolate, xylitol (from sugar-free gum), grapes, or certain medications. Ingesting non-food objects like socks, toys, or bones can also cause severe stomach irritation or blockage.
In these cases, drooling often happens due to nausea or mouth irritation, and vomiting may contain pieces of the ingested material. Blockages prevent food from passing normally, leading to pain, bloating, and refusal to eat.
Immediate veterinary care is critical in both situations — inducing vomiting or surgery may be required depending on the cause.
Dental or Oral Disease
Severe dental problems are often overlooked but can absolutely cause a dog to drool, feel sick, and stop eating.
Tooth abscesses, gum infections, or broken teeth make chewing painful, and oral bacteria can spread into the bloodstream, affecting internal organs. Drool may appear thick or bloody, and dogs may paw at their mouths or only eat soft food.
Regular dental check-ups, professional cleanings, and at-home brushing can prevent these painful issues. Once infection sets in, antibiotics and dental treatment are essential for recovery.
H4: Kidney Disease
Kidney disease can lead to nausea, drooling, vomiting, and complete loss of appetite. As the kidneys fail to filter waste properly, toxins build up, making the dog feel sick and lethargic.
You might notice increased thirst, frequent urination (or very little output), and a chemical odor on the breath.
Chronic kidney issues progress gradually, while acute kidney failure can appear suddenly after toxin ingestion or dehydration.
Early veterinary treatment can slow the progression and improve quality of life through diet, fluids, and medication.
Read more: Dog Being Sick and Not Eating and Lethargic (Here’s what it means)
What to Do If Your Dog Is Sick, Drooling, and Not Eating
If your dog is sick, drooling, and not eating, start by assessing how long the symptoms have lasted and whether there’s vomiting, diarrhea, or lethargy.
For mild, short-term stomach upset, you can withhold food for 8–12 hours (not water) to let the stomach settle. Afterward, offer small portions of boiled chicken and rice to test tolerance.
Keep your dog hydrated — dehydration worsens nausea and fatigue. You can offer ice cubes or a small amount of electrolyte solution if your vet approves.
If the drooling is accompanied by vomiting or your dog refuses food for more than 24 hours, contact your vet immediately. Never try to induce vomiting at home unless instructed, as some substances (like caustic chemicals or sharp objects) can cause severe damage when brought back up.
Maintain a calm environment. Stress can worsen nausea and delay recovery. Provide a quiet space and avoid forcing food or medication without veterinary guidance.
When to Call or Visit Your Vet
If your dog is drooling excessively, vomiting repeatedly, or hasn’t eaten for more than a day, it’s time to call your vet.
Seek emergency care if you notice signs like blood in vomit or stool, abdominal swelling, collapse, or seizures. These can indicate poisoning, pancreatitis, or internal bleeding.
Also, contact your vet urgently if drooling is accompanied by heavy panting, shaking, or pale gums — these could signal shock, toxin ingestion, or organ failure.
Early diagnosis can prevent serious complications. Diagnostic tests such as bloodwork, urinalysis, and imaging can pinpoint the cause and guide effective treatment.
Read more: Dog Being Sick and Drooling (Common causes explained)
Key Takeaway
A dog that’s sick, drooling, and not eating is almost always feeling nauseous or in pain — and often, the problem goes deeper than a simple upset stomach.
While minor digestive irritation may resolve with rest and hydration, persistent or severe symptoms require prompt veterinary care. The sooner your vet identifies the cause, the better your dog’s chances of a full and comfortable recovery.
When in doubt, always err on the side of caution — your dog’s drool may be their way of asking for help.