Panting accompanied by dilated pupils is a concerning symptom in dogs. When both signs appear together, it is important to take notice promptly, because they can signal a situation that requires urgent veterinary evaluation.
We outline the common causes of panting and dilated pupils in dogs, what you can do, and when to seek veterinary help.
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Dog Panting and Pupils Dilated — Why It Happens
Dog panting with dilated pupils often indicates stress, fear, excitement, or pain. These are part of the body’s natural “fight-or-flight” response, where adrenaline increases heart rate, widens pupils, and triggers panting to draw in more oxygen.
It can also occur due to heat, certain medications (like steroids or stimulants), or medical issues such as toxin exposure or neurological problems.

Dog Panting and Pupils Dilated: Common Causes
Pain or Discomfort
Pain is a frequent reason why dogs may pant with dilated pupils. When a dog experiences acute or chronic pain, the body responds by releasing stress hormones, leading to heavy panting and dilated pupils. Pain may be caused by injuries, arthritis, internal issues, or dental problems.
Signs to watch for include whimpering, reluctance to move, limping, guarding a body part, or sudden aggression. Promptly addressing pain is crucial, both for your dog’s comfort and to prevent secondary stress-related health problems.
Anxiety or Stress
Severe anxiety or stress can trigger panting and pupil dilation in dogs. Situations such as thunderstorms, fireworks, separation, or unfamiliar environments activate the dog’s sympathetic nervous system.
This “fight-or-flight” response increases heart rate, respiratory rate, and pupil size.
Other symptoms often include pacing, shaking, excessive licking, or hiding. While mild anxiety may be managed at home, chronic or extreme stress should be discussed with a veterinarian or canine behaviorist to ensure long-term well-being.
Neurological Disorders
Neurological issues can manifest as panting with dilated pupils. Conditions affecting the brain, spinal cord, or nerves—such as seizures, brain tumors, or encephalitis—can disrupt the autonomic nervous system, causing unusual pupil size and irregular breathing patterns.
Look for additional signs such as disorientation, tremors, head tilting, imbalance, or seizure activity.
Early veterinary evaluation is essential, as neurological problems can progress rapidly and may require advanced diagnostics and treatment.
Toxins or Poisoning
Ingestion of toxic substances can cause panting and dilated pupils in dogs. Certain medications, plants, human foods, or chemicals can affect the nervous system or cardiovascular system, resulting in these visible symptoms.
Other warning signs can include vomiting, diarrhea, drooling, agitation, or weakness. Immediate veterinary intervention is critical, as some toxins can be fatal if not treated promptly.
Painful or Severe Illnesses
Systemic illnesses such as kidney failure, liver disease, or infections may lead to panting and dilated pupils.
As the body struggles to maintain oxygen, blood pressure, and metabolic balance, signs like rapid breathing, disorientation, and abnormal pupil responses may appear.
Additional symptoms might include lethargy, vomiting, loss of appetite, or changes in urination.
Timely veterinary evaluation can detect underlying conditions early, improving outcomes and quality of life.
Shock or Low Blood Pressure
Shock or hypotension (low blood pressure) can cause both panting and dilated pupils. Trauma, severe blood loss, dehydration, or anaphylactic reactions reduce blood flow to vital organs.
The dog’s body compensates with rapid breathing and pupil dilation to maximize oxygen and alertness.
Signs often include pale or bluish gums, weakness, rapid heart rate, cold extremities, and collapse.
Shock is a medical emergency requiring immediate veterinary attention to stabilize the dog and address the underlying cause.
Heatstroke
Heatstroke may lead to panting with dilated pupils, particularly in hot weather or after strenuous activity.
Overheating affects circulation and neurological function, causing signs such as heavy panting, drooling, vomiting, disorientation, or unresponsiveness.
Brachycephalic breeds (short-nosed dogs) and elderly or overweight dogs are especially susceptible. Rapid cooling and emergency veterinary care are critical to prevent organ failure or death.
What to Do If Your Dog Is Panting and Pupils Dilated
Keep your dog in a calm, comfortable environment and avoid stressful situations.
Monitor your dog’s breathing, behavior, and pupil size, and take note of any accompanying signs like vomiting, lethargy, or disorientation.
Do not attempt home treatments for dilated pupils without veterinary guidance, as this symptom usually indicates a serious underlying issue.
Provide water if your dog is alert and able to drink safely, but avoid forcing fluids.
Seek immediate veterinary attention, bringing details about recent activity, diet, medications, or possible exposure to toxins to assist with diagnosis.
When to Call or Visit Your Vet
Contact your veterinarian immediately if your dog exhibits:
Persistent panting with dilated pupils
Weakness, collapse, or confusion
Vomiting, diarrhea, or signs of pain
Rapid or irregular heartbeat
Tremors, disorientation, or seizures
These symptoms may indicate life-threatening conditions. Prompt intervention can prevent worsening and improve recovery chances.
Read more: Dog lethargic not eating and red eyes (Causes explained)
Key Takeaway
Panting accompanied by dilated pupils is a serious symptom in dogs that may signal pain, anxiety, neurological disorders, poisoning, systemic illness, shock, or heatstroke.
Observing your dog closely, ensuring a calm environment, and seeking immediate veterinary care are essential steps.