If your dog is lethargic, not eating, and shaking, these symptoms together may indicate pain, fear, illness, or even a medical emergency. While each sign individually can sometimes be harmless, their combination suggests that your dog is not feeling well physically or emotionally. Because dogs can’t tell us what’s wrong, understanding what this behavior may mean is essential to helping them recover quickly and safely.
Dog Lethargic Not Eating and Shaking: Why It Happens
When your dog is lethargic not eating and shaking, the cause could range from pain, fever, internal illness, toxin ingestion, or emotional distress to more serious conditions like pancreatitis or neurological issues. The body may tremble in response to discomfort, chills, or shock, while fatigue and appetite loss suggest the dog’s system is overwhelmed.

Dog Lethargic Not Eating and Shaking: Common Causes
Pain or Physical Discomfort
Pain is one of the most common causes of shaking in dogs, especially when combined with lethargy and refusal to eat. Whether the pain is from arthritis, abdominal cramping, a recent injury, or dental issues, your dog may shake involuntarily and seem withdrawn.
Look for additional signs of pain such as limping, flinching when touched, whining, or a hunched posture. Pain management is essential—ignoring it can lead to further complications and distress.
Related: My dog is lethargic and not eating (Causes and when to worry)
Fever or Infection
If your dog is lethargic, not eating, and shaking, it could be running a fever. Just like in humans, fever in dogs can cause chills, body aches, and fatigue. Common causes include bacterial or viral infections such as parvovirus, leptospirosis, or even tick-borne illnesses.
Accompanying symptoms may include vomiting, diarrhea, nasal discharge, or swollen lymph nodes. If you suspect an infection, it’s crucial to get your dog to a veterinarian promptly for diagnosis and supportive care.
Pancreatitis
Pancreatitis often causes shaking, abdominal pain, lethargy, and a loss of appetite. This condition, which is inflammation of the pancreas, is usually triggered by high-fat foods or metabolic issues. Dogs experiencing an episode may shake due to severe internal discomfort or nausea.
This illness can be dangerous without treatment and typically requires fluid therapy, anti-nausea medication, and dietary changes. Breeds like Miniature Schnauzers and Poodles are especially prone to pancreatitis.
Toxin Exposure
Some toxins can cause both tremors and digestive symptoms like vomiting, diarrhea, and refusal to eat. Substances like chocolate, xylitol, pesticides, or certain human medications are highly dangerous to dogs.
Shaking may occur due to tremors, weakness, or neurological effects. Lethargy and appetite loss often follow shortly afterward. If you suspect your dog has ingested anything potentially harmful, this is an emergency—call your vet or poison control immediately.
Hypoglycemia (Low Blood Sugar)
In small-breed puppies, toy dogs, or diabetic pets, low blood sugar can lead to shaking, disorientation, lethargy, and appetite changes. This condition progresses quickly and can become life-threatening if not addressed.
If your dog is known to be at risk, you may be advised to offer a sugar solution like corn syrup to restore balance temporarily—but this should never replace proper veterinary care.
Stress or Anxiety
Sometimes, your dog may tremble and avoid food due to emotional triggers. Loud noises, unfamiliar environments, separation anxiety, or traumatic events can all cause shaking and withdrawal.
While emotional causes often resolve once your dog feels safe again, stress shouldn’t be overlooked—especially if shaking persists even after calming efforts. Persistent fear-based symptoms can also lead to physical exhaustion and lowered immune response.
Neurological Disorders
Although less common, certain neurological conditions such as seizures, vestibular disease, or degenerative disorders can cause dogs to shake, become unsteady, lose appetite, and appear lethargic.
If the shaking resembles muscle twitching, is localized (e.g., only in the head or legs), or is accompanied by confusion or uncoordinated movement, a neurological exam may be needed.
What to Do If Your Dog Is Lethargic Not Eating and Shaking
Here are some practical steps to take at home if your dog is experiencing these symptoms:
Check for visible injuries or swelling – Gently feel your dog’s body for any areas of pain or sensitivity.
Take temperature – If you have a pet thermometer, a dog’s normal rectal temperature is 101–102.5°F (38.3–39.2°C).
Offer water and bland food – If they refuse, don’t force it, but monitor if they’re able to drink at all.
Create a calm environment – Reduce noise and distractions to lower anxiety if fear or overstimulation is suspected.
Monitor symptom progression – Track when shaking started, how long it lasts, and whether it worsens over time.
If symptoms persist for more than a few hours, or if they worsen rapidly, don’t delay in contacting your vet.
When to Call or Visit Your Vet
You should seek immediate veterinary care if:
Your dog shakes continuously for more than 30 minutes
Vomiting, diarrhea, or seizures occur alongside shaking
Your dog refuses all food and water
They collapse, become unresponsive, or seem disoriented
You suspect toxin ingestion or trauma
Prompt evaluation can make all the difference—especially if the cause is something acute like pancreatitis or toxin exposure.
Related: Dog Lethargic Not Eating and Vomiting
Read more: Dog Lethargic Not Eating and Diarrhea
Final Thoughts
If your dog is lethargic, not eating, and shaking, it’s more than just a rough day—it’s a combination of symptoms that may signal pain, illness, or even a medical emergency. While some causes may be mild and resolve with rest, others require swift veterinary attention. Your observations and quick action could make a huge difference in your dog’s recovery and comfort. Always trust your gut—when in doubt, reach out to your vet.